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Diazepam is N-demethylated by CYP3A4 and 2C19 into the Lively metabolite N-desmethyldiazepam, and it is hydroxylated by CYP3A4 towards the active metabolite temazepam. N-desmethyldiazepam and temazepam are each even further metabolized to oxazepam. Temazepam and oxazepam are mainly eradicated by glucuronidation.Diazepam does not have any chiral fac

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